IV Vitamin C Injections

TruMed offers Edmonton IV Vitamin C - think immunity, longevity, cosmetics and cancer.

Vitamin C IV Facts

IV vitamin C bypasses intestinal absorption and the associated saturable transport mechanisms in the digestive tract. Intravenous vitamin C might reach blood concentrations that are up to 100 times higher than the same oral dose

In a 2004 study where 12 adults were given 1.25 grams of vitamin C either orally or intravenously (we'd consider this a baby dose in terms of IV Vitamin C) peak plasma concentrations reached 135 micromoles/L with oral administration but it reached 885 micromoles/L with intravenous administration. 

By providing Vitamin C intravenously with IV therapy our Naturopathic doctors can give you levels of Vitamin C that you simply won't get any other way. 

Our standard Myers Cocktail IV has 2.5 grams of Vitamin C, whereas our IV treatments for infections for instance are anywhere from 10-30 grams of Vitamin C

Vitamin C is highly concentrated in immune cells, with neutrophils and leukocytes having 50 to 100 times higher vitamin C concentrations than the blood. 

The innate immune system of the lungs protects the body from inhaled oxidants and pathogens. Vitamin C helps protect the lungs by boosting immune cell function and reducing oxidative stress.  In March 2020 there was a reasonable amount of data released from China discussing IV Vitamin C for COVID-19 treatment. 

One group has proposed "the utilization of hyperbaric oxygen therapy immediate­ly after IV vitamin C therapy to increase its effectiveness as an anticancer agent",  this recommendation was presumably in order to increase the formation of hydrogen per­oxide from the IV Vitamin C Therapy.

NAD+ IV Injection

Our Naturopathic Doctors consider NAD+ IV Therapy for Fatigue, Longevity & Withdrawal

NAD+ IV Facts

Warning! Boring bio-chemistry ahead! Mammals have seven sirtuins (SIRT1–7) which are involved in a process called de-acetylation and subsequently have a role in longevity. Sirtuins, require NAD+ as a cofactor.

NAD+ can stimulate energy production by replenishing depleted cellular stores of ATP - our bodies' main energy currency.  NAD+ is reduced (gains an electron) to NADH by the enzymes of the tricarboxylic acid/citric acid (TCA) cycle before being re-oxidized to NAD+ (loses an electron - hence the +). See this awesome post on NAD if you want more detail on the biochemistry of NAD.

By providing NAD+ intravenously with IV therapy our Naturopathic doctors provide additional substrate for ATP production and in some patients this can produce profound increases in energy. 

With regards to information about NAD+ and its use in addiction and recovery, the original research appears to have come from authors Block and Broom, giving patients NAD and an amino acid formula for 10 consecutive days ranging from 5 to 10 hours daily, to significantly lessen withdrawal from a variety of drugs and alcohol. Our Naturopaths usually spike the NAD IV with additional nutrients and a ton of Vitamin C to ease withdrawal.

A 2019 study published on NAD+ given IV after a 6 Hour Intravenous Infusion of NAD+ from Dr Broom.

Mechanistically we can expect strong synergy between IV NAD and Hyperbaric chamber treatment because of the dual action on the Krebs Cycle and electron transport chain respectively.

Myers Cocktail IV

Our Naturopaths have given thousands of IV Myers Cocktails in Edmonton.

Background:

Who was Myers? Apparently from the late 1950s to 1984, Dr. John Myers MD in the Baltimore area was administering Vitamin pushes to his patients to fatigue, depression, angina and infections. A Vitamin push simply means administering an IV manually with a syringe instead of an IV bag.  

In 1984, Myers had passed away and a number of his patients came to the office of Dr. Alan Gaby MD requesting that same IV. 

The exact doses were not known, however the ingredients somewhat were and Dr Gaby formulated his own version of the treatment and also began administering the treatment to other patients for other conditions. Dr Gaby ended up popularizing the treatment through presentations on his results at medical conferences and seminars. 

Dr Gaby gave 15,000 of these injections to an estimated 800–1,000 different patients. 

Dr Muradov devised his own formulation of the Myers, the "Advanced Myers" that's evolved over 9 years of administration that's given as a small bolus IV that has higher doses of most of the B Vitamins as well as added Riboflavin - Vitamin B2 (was not part of the original IV).

So what's the Myers used for? Dr. Gaby found it useful for the following conditions: Fatigue, Migraine, Asthma, Fibromyalgia, Depression, Upper Respiratory Tract Infections, Seasonal Allergy, Narcotic Withdrawal, Chronic Hives, Athletic Performance, Hyperthyroidism and COPD. 

Our Naturopaths have verified every one of his findings in our Edmonton patients. 

We expect additive action between administration of the Myers IV Therapy and Hyperbaric treatment because of mechanistic overlap between the Krebs cycle (of which the Myers provides substrate) and the ETC of which oxygen is the final electron acceptor in ATP production. 

Check out our Myers section for more information on this kick ass treatment.

Dr Gaby's Article in AltMed Review

Glutathione IV Therapy

Our Naturopathic Doctors offer Edmonton a number of IV Glutathione options

Glutathione Facts

Glutathione is the major intracellular antioxidant. It has numerous functions including protecting cells against oxidative stress, detoxification of toxins and carcinogens, and maintenance of immune function. Nearly, all tissues in the body synthesize Glutathione "GSH".

Glutathione is produced from three amino acids—glutamate, cysteine and glycine so our Naturopath often give our Edmonton patients N-Acetyl-Cysteine (NAC) to increase Glutathione production in-between Glutathione IVs.

Glutathione is distributed throughout the human body. The highest levels are found in the liver, followed by the kidney, spleen, small intestine, brain, pancreas, lung, heart, and muscle respectively. 

Glutathione does not reach the brain directly because of the blood-brain barrier (BBB), it can penetrate the BBB only by the mechanism of passive diffusion. Which is partly why glutathione is given as a push style IV, to create a strong concentration gradient to enter the nervous system.

Low GSH levels are associated with increased risks of numerous diseases including cancer, cardiovascular diseases, arthritis and diabetes. 

Accumulating lines of evidence indicate that glutathione function is implicated in some neurodegenerative diseases such as Alzheimer’s disease, Parkinson’s disease, ALS, Huntington’s disease, and Multiple Sclerosis. We often give glutathione IV therapy for acute exacerbations of Multiple Sclerosis at our Edmonton Naturopath Clinic, as well as for ALS & Lyme. 

The skin lightening properties result from a variety of mechanisms including stimulation of lighter pheomelanin pigment synthesis rather than darker eumelanin. For cosmetic purposes, our Naturopathic Doctors combine IV Glutathione with IV Vitamin C. 

IV Glutathione is recommended as part of a head injury protocol in addition to IV Nutrients and LAMC/Lipoic acid IV paired with Hyperbaric Chamber therapy by Paul Anderson ND. 

Curcumin IV

We offer Curcumin IV Therapy for inflammation and cancer support

Curcumin IV Facts

Curcumin is a yellowish pigment and a well-known polyphenol found in turmeric (Curcuma longa). The variety of health properties such as antioxidant, anti-inflammatory, anti-cancer, antidiabetic, hepatoprotective, anti-allergic, and neuroprotective effects have been attributed to Curcumin. 

Warning! BORING: From a molecular point of view, curcumin may mediate its pharmacological activities through JAK-STAT, NFkB, Nrf2, AKT, TGF-b and mTOR. 

In particular, curcumin inhibits the transcription factor NF-kB and mediates its anti-inflammatory action and the induction of Nrf2 signaling pathways promotes antioxidant defense mechanisms and production of phase II liver enzymes. Anticarcinogenic effects of curcumin are in part also related to an increase in the p53 levels. 

With regards to cancer, in one trial, with Colon Cancer patients, curcumin given in advanced colorectal cancer patients refractory to standard chemotherapies resulted in stable disease for 2-4 months in five of fifteen patients. Our Naturopaths strongly consider the use of IV therapy with Curcumin in Colon and Pancreatic cancer in particular. 

With regards to pain, in an Arthritis trial, 100 patients were given Curcumin therapy for 8 months. Significant improvements of both the clinical and blood marker end points were observed for the curcumin group compared to the control group. Our Naturopathic Doctors sometimes use IV therapy with Curcumin as an induction therapy for advanced cases of Arthritis and then transition patients to oral high dose, bio-available Curcumin preparations.

Generally, the oral bioavailability of curcumin is low due to a relatively low absorption by small intestine coupled to an extensive reductive and conjugative metabolism in the liver and an elimination through the gall bladder. Which is why IV Therapy administration of Curcumin is the ideal way to get the amazing benefits of Curcumin, especially in cancer patients. However our Naturopathic doctors do make use of some newer oral more bio-available Curcumin preparations. As of 2020, Dr Muradov's preferred oral Curcumin is Curcumin Ultra from AOR - it has awesome data on its absorption and utilization as a free Curcumin.